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Studies indicate that first-degree relatives of women with endometriosis will more likely acquire this disease. When there is a genetic link, the disease is more often than not, worse in the subsequent generation.

When endometriosis affects the reproductive organs, then fertility is compromised. 30 – 40% of women with endometriosis are infertile. Endometriosis is also be subtle in the way it affects womens bodies. Recent studies indicate that the simple presence of this disease, whether it is, mild or minimal, at any stage, may be to blame for implantation and immune system problems in some women. Studies have shown that women with endometriosis have an elevated risk for increased levels of APA (antiphospholipid antibodies), which is linked to continuing miscarriage, intrauterine growth retardation, and pre- eclampsia. Other, even more subtle effects, are caused by endometriosis. It may increase the macrophages (natural scavenger cells) in peritoneal fluid which may kill off sperm, egg, or embryo. One study linked endometriosis with production of poorer quality eggs